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Intracellular Kinases Mediate Increased Translation and Secretion of Netrin-1 from Renal Tubular Epithelial Cells

BACKGROUND: Netrin-1 is a laminin-related secreted protein, is highly induced after tissue injury, and may serve as a marker of injury. However, the regulation of netrin-1 production is not unknown. Current study was carried out in mouse and mouse kidney cell line (TKPTS) to determine the signaling...

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Detalles Bibliográficos
Autores principales: Jayakumar, Calpurnia, Mohamed, Riyaz, Ranganathan, Punithavathi Vilapakkam, Ramesh, Ganesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202578/
https://www.ncbi.nlm.nih.gov/pubmed/22046354
http://dx.doi.org/10.1371/journal.pone.0026776