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Nebulisation of Receptor-Targeted Nanocomplexes for Gene Delivery to the Airway Epithelium
BACKGROUND: Gene therapy mediated by synthetic vectors may provide opportunities for new treatments for cystic fibrosis (CF) via aerosolisation. Vectors for CF must transfect the airway epithelium efficiently and not cause inflammation so they are suitable for repeated dosing. The inhaled aerosol sh...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202583/ https://www.ncbi.nlm.nih.gov/pubmed/22046351 http://dx.doi.org/10.1371/journal.pone.0026768 |