Sox9 Transcriptionally Represses Spp1 to Prevent Matrix Mineralization in Maturing Heart Valves and Chondrocytes

Sox9 is an SRY-related transcription factor required for expression of cartilaginous genes in the developing skeletal system and heart valve structures. In contrast to positively regulating cartilaginous matrix, Sox9 also negatively regulates matrix mineralization associated with bone formation. Whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Peacock, Jacqueline D., Huk, Danielle J., Ediriweera, Hasini N., Lincoln, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202586/
https://www.ncbi.nlm.nih.gov/pubmed/22046352
http://dx.doi.org/10.1371/journal.pone.0026769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202586/
https://www.ncbi.nlm.nih.gov/pubmed/22046352
http://dx.doi.org/10.1371/journal.pone.0026769

Ejemplares similares