c-Kit-Mediated Functional Positioning of Stem Cells to Their Niches Is Essential for Maintenance and Regeneration of Adult Hematopoiesis

The mechanism by which hematopoietic stem and progenitor cells (HSPCs) through interaction with their niches maintain and reconstitute adult hematopoietic cells is unknown. To functionally and genetically track localization of HSPCs with their niches, we employed novel mutant loxPs, lox66 and lox71...

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Detalles Bibliográficos
Autores principales: Kimura, Yuki, Ding, Bisen, Imai, Norikazu, Nolan, Daniel J., Butler, Jason M., Rafii, Shahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202594/
https://www.ncbi.nlm.nih.gov/pubmed/22046410
http://dx.doi.org/10.1371/journal.pone.0026918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202594/
https://www.ncbi.nlm.nih.gov/pubmed/22046410
http://dx.doi.org/10.1371/journal.pone.0026918

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