Novel Vaginal Microflora Colonization Model Providing New Insight into Microbicide Mechanism of Action

Several broad-spectrum microbicides, including cellulose sulfate (CS), have passed conventional preclinical and phase I clinical safety evaluation and yet have failed to protect women from acquiring HIV-1 in phase II/III trials. Concerns have been raised that current preclinical algorithms are defic...

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Detalles Bibliográficos
Autores principales: Fichorova, Raina N., Yamamoto, Hidemi S., Delaney, Mary L., Onderdonk, Andrew B., Doncel, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202752/
https://www.ncbi.nlm.nih.gov/pubmed/22027006
http://dx.doi.org/10.1128/mBio.00168-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202752/
https://www.ncbi.nlm.nih.gov/pubmed/22027006
http://dx.doi.org/10.1128/mBio.00168-11

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