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Pasteurella multocida Toxin Activates Various Heterotrimeric G Proteins by Deamidation

Pasteurella multocida produces a 146-kDa protein toxin (Pasteurella multocida toxin, PMT), which stimulates diverse cellular signal transduction pathways by activating heterotrimeric G proteins. PMT deamidates a conserved glutamine residue of the α-subunit of heterotrimeric G proteins that is essent...

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Detalles Bibliográficos
Autores principales: Orth, Joachim H. C., Aktories, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202810/
https://www.ncbi.nlm.nih.gov/pubmed/22069582
http://dx.doi.org/10.3390/toxins2020205