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G(i/o) Protein-Dependent and -Independent Actions of Pertussis Toxin (PTX)

Pertussis toxin (PTX) is a typical A-B toxin. The A-protomer (S1 subunit) exhibits ADP-ribosyltransferase activity. The B-oligomer consists of four subunits (S2 to S5) and binds extracellular molecules that allow the toxin to enter the cells. The A-protomer ADP-ribosylates the α subunits of heterotr...

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Detalles Bibliográficos
Autores principales: Mangmool, Supachoke, Kurose, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202852/
https://www.ncbi.nlm.nih.gov/pubmed/22069745
http://dx.doi.org/10.3390/toxins3070884