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Immunotoxins and Anticancer Drug Conjugate Assemblies: The Role of the Linkage between Components

Immunotoxins and antibody-drug conjugates are protein-based drugs combining a target-specific binding domain with a cytotoxic domain. Such compounds are potentially therapeutic against diseases including cancer, and several clinical trials have shown encouraging results. Although the targeted elimin...

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Detalles Bibliográficos
Autores principales: Dosio, Franco, Brusa, Paola, Cattel, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202854/
https://www.ncbi.nlm.nih.gov/pubmed/22069744
http://dx.doi.org/10.3390/toxins3070848