Isolation and Biochemical Characterization of Rubelase, a Non-Hemorrhagic Elastase from Crotalus ruber ruber (Red Rattlesnake) Venom

A novel non-hemorrhagic basic metalloprotease, rubelase, was isolated from the venom of Crotalus ruber ruber. Rubelase hydrolyzes succinyl-L-alanyl-L-alanyl-L-alanyl p-nitroanilide (STANA), a specific substrate for elastase, and the hydrolytic activity was inhibited by chelating agents. It also hydr...

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Detalles Bibliográficos
Autores principales: Komori, Yumiko, Sakai, Kaname, Masuda, Katsuyoshi, Nikai, and Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202862/
https://www.ncbi.nlm.nih.gov/pubmed/22069746
http://dx.doi.org/10.3390/toxins3070900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202862/
https://www.ncbi.nlm.nih.gov/pubmed/22069746
http://dx.doi.org/10.3390/toxins3070900

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