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Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells
Glycosyltransferases (GTs) are ubiquitous enzymes that catalyze the assembly of glycoconjugates found throughout all kingdoms of nature. A longstanding problem is the rational design of probes that can be used to manipulate GT activity in cells and tissues. Here we describe the rational design and s...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202988/ https://www.ncbi.nlm.nih.gov/pubmed/21258330 http://dx.doi.org/10.1038/nchembio.520 |