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Toll-like receptor 2 -196 to -174 del polymorphism influences the susceptibility of Han Chinese people to Alzheimer's disease

BACKGROUND: Toll-like receptor 2 (TLR2) represents a reasonable functional and positional candidate gene for Alzheimer's disease (AD) as it is located under the linkage region of AD on chromosome 4q, and functionally is involved in the microglia-mediated inflammatory response and amyloid-β clea...

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Detalles Bibliográficos
Autores principales: Yu, Jin-Tai, Mou, Shan-Mao, Wang, Li-Zhu, Mao, Cai-Xia, Tan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203069/
https://www.ncbi.nlm.nih.gov/pubmed/21989233
http://dx.doi.org/10.1186/1742-2094-8-136