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RAGE and ICAM-1 differentially control leukocyte recruitment during acute inflammation in a stimulus-dependent manner

BACKGROUND: The receptor for advanced glycation endproducts, RAGE, is involved in the pathogenesis of many inflammatory conditions, which is mostly related to its strong activation of NF-κB but also due to its function as ligand for the β(2)-integrin Mac-1. To further dissect the stimulus-dependent...

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Detalles Bibliográficos
Autores principales: Frommhold, David, Kamphues, Anna, Dannenberg, Susanne, Buschmann, Kirsten, Zablotskaya, Victoria, Tschada, Raphaela, Lange-Sperandio, Baerbel, Nawroth, Peter P, Poeschl, Johannes, Bierhaus, Angelika, Sperandio, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203087/
https://www.ncbi.nlm.nih.gov/pubmed/21970746
http://dx.doi.org/10.1186/1471-2172-12-56