Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits

The brain contains numerous mononuclear phagocytes called microglia. These cells express the transmembrane tyrosine kinase receptor for the macrophage growth factor colony stimulating factor-1 (CSF-1R). Using a CSF-1R-GFP reporter mouse strain combined with lineage defining antibody staining we show...

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Detalles Bibliográficos
Autores principales: Erblich, Bryna, Zhu, Liyin, Etgen, Anne M., Dobrenis, Kostantin, Pollard, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203114/
https://www.ncbi.nlm.nih.gov/pubmed/22046273
http://dx.doi.org/10.1371/journal.pone.0026317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203114/
https://www.ncbi.nlm.nih.gov/pubmed/22046273
http://dx.doi.org/10.1371/journal.pone.0026317

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