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Overexpression of Active Aurora-C Kinase Results in Cell Transformation and Tumour Formation

Aurora kinases belong to a conserved family of serine/threonine kinases key regulators of cell cycle progression. Aurora-A and Aurora-B are expressed in somatic cells and involved mainly in mitosis while Aurora-C is expressed during spermatogenesis and oogenesis and is involved in meiosis. Aurora-C...

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Detalles Bibliográficos
Autores principales: Khan, Jabbar, Ezan, Frédéric, Crémet, Jean-Yves, Fautrel, Alain, Gilot, David, Lambert, Marine, Benaud, Christelle, Troadec, Marie-Bérengère, Prigent, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203144/
https://www.ncbi.nlm.nih.gov/pubmed/22046298
http://dx.doi.org/10.1371/journal.pone.0026512