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Paromomycin Affects Translation and Vesicle-Mediated Trafficking as Revealed by Proteomics of Paromomycin –Susceptible –Resistant Leishmania donovani

Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis (VL) and is responsible for significant mortality and morbidity. Increasing resistance towards antimonial drugs poses a great challenge in chemotherapy of VL. Paromomycin is an aminoglycosidic antibiotic and is one of the...

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Detalles Bibliográficos
Autores principales: Chawla, Bhavna, Jhingran, Anupam, Panigrahi, Aswini, Stuart, Kenneth D., Madhubala, Rentala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203147/
https://www.ncbi.nlm.nih.gov/pubmed/22046323
http://dx.doi.org/10.1371/journal.pone.0026660