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Increased Lipolysis and Energy Expenditure in a Mouse Model with Severely Impaired Glucagon Secretion

BACKGROUND: Secretion of insulin and glucagon is triggered by elevated intracellular calcium levels. Although the precise mechanism by which the calcium signal is coupled to insulin and glucagon granule exocytosis is unclear, synaptotagmin-7 has been shown to be a positive regulator of calcium-depen...

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Detalles Bibliográficos
Autores principales: Lou, Phing-How, Gustavsson, Natalia, Wang, Yue, Radda, George K., Han, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203149/
https://www.ncbi.nlm.nih.gov/pubmed/22046328
http://dx.doi.org/10.1371/journal.pone.0026671