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Increased Lipolysis and Energy Expenditure in a Mouse Model with Severely Impaired Glucagon Secretion
BACKGROUND: Secretion of insulin and glucagon is triggered by elevated intracellular calcium levels. Although the precise mechanism by which the calcium signal is coupled to insulin and glucagon granule exocytosis is unclear, synaptotagmin-7 has been shown to be a positive regulator of calcium-depen...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203149/ https://www.ncbi.nlm.nih.gov/pubmed/22046328 http://dx.doi.org/10.1371/journal.pone.0026671 |