The Role of Endosomal Escape and Mitogen-Activated Protein Kinases in Adenoviral Activation of the Innate Immune Response

Adenoviral vectors (AdV) activate multiple signaling pathways associated with innate immune responses, including mitogen-activated protein kinases (MAPKs). In this study, we investigated how systemically-injected AdVs activate two MAPK pathways (p38 and ERK) and the contribution of these kinases to...

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Detalles Bibliográficos
Autores principales: Smith, Jeffrey S., Xu, Zhili, Tian, Jie, Palmer, Donna J., Ng, Philip, Byrnes, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203151/
https://www.ncbi.nlm.nih.gov/pubmed/22046344
http://dx.doi.org/10.1371/journal.pone.0026755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203151/
https://www.ncbi.nlm.nih.gov/pubmed/22046344
http://dx.doi.org/10.1371/journal.pone.0026755

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