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Non-Hematopoietic Cells in Lymph Nodes Drive Memory CD8 T Cell Inflation during Murine Cytomegalovirus Infection

During human and murine cytomegalovirus (MCMV) infection an exceptionally large virus-specific CD8 T cell pool is maintained in the periphery lifelong. This anomalous response is only seen for specific subsets of MCMV-specific CD8 T cells which are referred to as 'inflationary T cells'. Ho...

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Detalles Bibliográficos
Autores principales: Torti, Nicole, Walton, Senta M., Brocker, Thomas, Rülicke, Thomas, Oxenius, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203160/
https://www.ncbi.nlm.nih.gov/pubmed/22046127
http://dx.doi.org/10.1371/journal.ppat.1002313