Herpesvirus Telomerase RNA (vTR) with a Mutated Template Sequence Abrogates Herpesvirus-Induced Lymphomagenesis

Telomerase reverse transcriptase (TERT) and telomerase RNA (TR) represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation...

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Detalles Bibliográficos
Autores principales: Kaufer, Benedikt B., Arndt, Sina, Trapp, Sascha, Osterrieder, Nikolaus, Jarosinski, Keith W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203187/
https://www.ncbi.nlm.nih.gov/pubmed/22046133
http://dx.doi.org/10.1371/journal.ppat.1002333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203187/
https://www.ncbi.nlm.nih.gov/pubmed/22046133
http://dx.doi.org/10.1371/journal.ppat.1002333

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