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Herpesvirus Telomerase RNA (vTR) with a Mutated Template Sequence Abrogates Herpesvirus-Induced Lymphomagenesis
Telomerase reverse transcriptase (TERT) and telomerase RNA (TR) represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation...
Autores principales: | Kaufer, Benedikt B., Arndt, Sina, Trapp, Sascha, Osterrieder, Nikolaus, Jarosinski, Keith W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203187/ https://www.ncbi.nlm.nih.gov/pubmed/22046133 http://dx.doi.org/10.1371/journal.ppat.1002333 |
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