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IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic Entry

To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon inducible transmembrane protein family members, IFITM1, 2 and 3, are IEGs required...

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Detalles Bibliográficos
Autores principales: Feeley, Eric M., Sims, Jennifer S., John, Sinu P., Chin, Christopher R., Pertel, Thomas, Chen, Li-Mei, Gaiha, Gaurav D., Ryan, Bethany J., Donis, Ruben O., Elledge, Stephen J., Brass, Abraham L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203188/
https://www.ncbi.nlm.nih.gov/pubmed/22046135
http://dx.doi.org/10.1371/journal.ppat.1002337