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Leishmania Mitochondrial Peroxiredoxin Plays a Crucial Peroxidase-Unrelated Role during Infection: Insight into Its Novel Chaperone Activity

Two-cysteine peroxiredoxins are ubiquitous peroxidases that play various functions in cells. In Leishmania and related trypanosomatids, which lack catalase and selenium-glutathione peroxidases, the discovery of this family of enzymes provided the molecular basis for peroxide removal in these organis...

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Detalles Bibliográficos
Autores principales: Castro, Helena, Teixeira, Filipa, Romao, Susana, Santos, Mariana, Cruz, Tânia, Flórido, Manuela, Appelberg, Rui, Oliveira, Pedro, Ferreira-da-Silva, Frederico, Tomás, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203189/
https://www.ncbi.nlm.nih.gov/pubmed/22046130
http://dx.doi.org/10.1371/journal.ppat.1002325