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Balanced gene regulation by an embryonic brain non-coding RNA is critical for GABA circuitry in adult hippocampus

Genomic studies demonstrate that while the majority of the mammalian genome is transcribed, only about 2% of these transcripts are protein coding. We have been investigating how the long, polyadenylated Evf2 non-coding RNA regulates transcription of homeodomain transcription factors DLX5 and DLX6 in...

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Detalles Bibliográficos
Autores principales: Bond, Allison M., VanGompel, Michael J.W., Sametsky, Evgeny A., Clark, Mary F., Savage, Julie C., Disterhoft, John F., Kohtz, Jhumku D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203213/
https://www.ncbi.nlm.nih.gov/pubmed/19620975
http://dx.doi.org/10.1038/nn.2371