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The HIV-1 gp120/V3 modifies the response of uninfected CD4 T cells to antigen presentation: mapping of the specific transcriptional signature

BACKGROUND: The asymptomatic phase of HIV-1 infection is characterized by a progressive depletion of uninfected peripheral effector/memory CD4+ T cells that subsequently leads to immune dysfunction and AIDS symptoms. We have previously demonstrated that the presence of specific gp120/V3 peptides dur...

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Detalles Bibliográficos
Autores principales: Morou, Antigone K, Porichis, Filippos, Krambovitis, Elias, Sourvinos, George, Spandidos, Demetrios A, Zafiropoulos, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203262/
https://www.ncbi.nlm.nih.gov/pubmed/21943198
http://dx.doi.org/10.1186/1479-5876-9-160