Cargando…

The HIV-1 gp120/V3 modifies the response of uninfected CD4 T cells to antigen presentation: mapping of the specific transcriptional signature

BACKGROUND: The asymptomatic phase of HIV-1 infection is characterized by a progressive depletion of uninfected peripheral effector/memory CD4+ T cells that subsequently leads to immune dysfunction and AIDS symptoms. We have previously demonstrated that the presence of specific gp120/V3 peptides dur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morou, Antigone K, Porichis, Filippos, Krambovitis, Elias, Sourvinos, George, Spandidos, Demetrios A, Zafiropoulos, Alexandros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203262/ https://www.ncbi.nlm.nih.gov/pubmed/21943198 http://dx.doi.org/10.1186/1479-5876-9-160

Ejemplares similares

Peripheral monocytes from diabetic patients with coronary artery disease display increased bFGF and VEGF mRNA expression
por: Panutsopulos, Dimitrios, et al.
Publicado: (2003)

Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties
por: López de Victoria, Aliana, et al.
Publicado: (2012)

Evaluation of STANDARD(TM) M10 SARS-CoV-2 assay as a diagnostic tool for SARS-CoV-2 in nasopharyngeal or oropharyngeal swab samples
por: Parakatselaki, Maria-Eleni, et al.
Publicado: (2023)

Miliary tuberculosis with no pulmonary involvement in myelodysplastic syndromes: a curable, yet rarely diagnosed, disease: case report and review of the literature
por: Neonakis, Ioannis K, et al.
Publicado: (2008)

Antigen processing sites in gp120 are conserved across HIV virus clades
por: Yu, B, et al.
Publicado: (2012)

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120
por: Yolitz, Jason, et al.
Publicado: (2018)

Rate and affinity binding constants determined by SPR spectroscopy reveal differential antigenicity of HIV gp120 and gp140
por: Gearhart, TL, et al.
Publicado: (2012)

HIV-1 Specific IgA Detected in Vaginal Secretions of HIV Uninfected Women Participating in a Microbicide Trial in Southern Africa Are Primarily Directed Toward gp120 and gp140 Specificities
por: Seaton, Kelly E., et al.
Publicado: (2014)

Ras Genes in Human Breast Cancer
por: Miyakis, Spiros, et al.
Publicado: (1999)

The paediatric story of human papillomavirus (Review)
por: MAMMAS, IOANNIS N., et al.
Publicado: (2014)

Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice
por: Moss, Emaya M., et al.
Publicado: (2023)

Antigenic Properties of the Human Immunodeficiency Virus Envelope Glycoprotein Gp120 on Virions Bound to Target Cells
por: Mengistu, Meron, et al.
Publicado: (2015)

Eliciting neutralizing antibodies with gp120 outer domain
por: Qin, Y, et al.
Publicado: (2012)

Internalization and Axonal Transport of the HIV Glycoprotein gp120
por: Berth, Sarah, et al.
Publicado: (2015)

Allosteric Modulation of the HIV-1 gp120-gp41 Association Site by Adjacent gp120 Variable Region 1 (V1) N-Glycans Linked to Neutralization Sensitivity
por: Drummer, Heidi E., et al.
Publicado: (2013)

Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 ± IL-15
por: McKee, Hayley J, et al.
Publicado: (2004)

Development of Protein- and Peptide-Based HIV Entry Inhibitors Targeting gp120 or gp41
por: Pu, Jing, et al.
Publicado: (2019)

Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface
por: Torrents de la Peña, Alba, et al.
Publicado: (2021)

COVID-19 pandemic: Monitoring space-time data and learning from global experience
por: Symvoulakis, Emmanouil K., et al.
Publicado: (2020)

Infiltration of dendritic cells and antigen uptake in the muscle after injection of HIV-1 Env gp120 in adjuvant
por: Liang, F, et al.
Publicado: (2012)

Correction: Antigenic Properties of the Human Immunodeficiency Virus Envelope Glycoprotein Gp120 on Virions Bound to Target Cells
Publicado: (2015)

The Downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 Axis and by Human Cytomegalovirus (HCMV) Associated Factors Allows the Activation of the HCMV Major IE Promoter and the Transition to Productive Infection
por: Sourvinos, George, et al.
Publicado: (2014)

NMR spectroscopy of HIV-1 gp120 outer domain
por: Sastry, M, et al.
Publicado: (2012)

Behavioral Evidence for a Tau and HIV-gp120 Interaction
por: Vijayan, Murali, et al.
Publicado: (2022)

Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides
por: Kassler, Kristin, et al.
Publicado: (2011)

Mapping the immune response to the outer domain of a human immunodeficiency virus-1 clade C gp120
por: Chen, Hongying, et al.
Publicado: (2008)

Evolution of the HIV-1 envelope glycoproteins with a disulfide bond between gp120 and gp41
por: Sanders, Rogier W, et al.
Publicado: (2004)

Sequential Immunization with gp140 Boosts Immune Responses Primed by Modified Vaccinia Ankara or DNA in HIV-Uninfected South African Participants
por: Churchyard, Gavin, et al.
Publicado: (2016)

Selected amino acid mutations in HIV-1 B subtype gp41 are Associated with Specific gp120(V3 )signatures in the regulation of Co-Receptor usage
por: Dimonte, Salvatore, et al.
Publicado: (2011)

Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response
por: Visciano, Maria Luisa, et al.
Publicado: (2008)

Interaction of the gp120 V1V2 loop with a neighboring gp120 unit shields the HIV envelope trimer against cross-neutralizing antibodies
por: Rusert, Peter, et al.
Publicado: (2011)

Deletion of the Highly Conserved N-Glycan at Asn260 of HIV-1 gp120 Affects Folding and Lysosomal Degradation of gp120, and Results in Loss of Viral Infectivity
por: Mathys, Leen, et al.
Publicado: (2014)

Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector
por: Khattar, Sunil K., et al.
Publicado: (2013)

Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding
por: Panico, Maria, et al.
Publicado: (2016)

HLA-C increases HIV-1 infectivity and is associated with gp120
por: Matucci, Andrea, et al.
Publicado: (2008)

The C5 region of HIV-1 gp120 binds specific
por: Dalgleish, A, et al.
Publicado: (2006)

Nitric oxide protects against HIV gp120 endothelial injury
por: Fiorucci, S, et al.
Publicado: (2010)

Structural Plasticity and Conformational Transitions of HIV Envelope Glycoprotein gp120
por: Korkut, Anil, et al.
Publicado: (2012)

Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate
por: Stansell, Elizabeth, et al.
Publicado: (2015)

Helix-A peptide prevents gp120-mediated neuronal loss
por: Avdoshina, Valeria, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ombgui43fi0h0bqh3guvpcr01l