STING is a direct innate immune sensor of cyclic-di-GMP

The innate immune system detects infection by employing germline-encoded receptors specific for conserved microbial molecules. Recognition of microbial ligands leads to the production of cytokines, such as type I interferons (IFN), that are essential for successful pathogen elimination. Cytosolic de...

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Detalles Bibliográficos
Autores principales: Burdette, Dara L., Monroe, Kathryn M., Sotelo-Troha, Katia, Iwig, Jeff S., Eckert, Barbara, Hyodo, Mamoru, Hayakawa, Yoshihiro, Vance, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203314/
https://www.ncbi.nlm.nih.gov/pubmed/21947006
http://dx.doi.org/10.1038/nature10429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203314/
https://www.ncbi.nlm.nih.gov/pubmed/21947006
http://dx.doi.org/10.1038/nature10429

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