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Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso

BACKGROUND: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs may influence the disease risk individually (main effects) or behave jointly (epistatic interactions). For the analysis of...

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Detalles Bibliográficos
Autores principales: Yang, Can, Wan, Xiang, Yang, Qiang, Xue, Hong, Yu, Weichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203332/
https://www.ncbi.nlm.nih.gov/pubmed/20122189
http://dx.doi.org/10.1186/1471-2105-11-S1-S18