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Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
BACKGROUND: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs may influence the disease risk individually (main effects) or behave jointly (epistatic interactions). For the analysis of...
Autores principales: | Yang, Can, Wan, Xiang, Yang, Qiang, Xue, Hong, Yu, Weichuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203332/ https://www.ncbi.nlm.nih.gov/pubmed/20122189 http://dx.doi.org/10.1186/1471-2105-11-S1-S18 |
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