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Quality control in the initiation of eukaryotic DNA replication

Origins of DNA replication must be regulated to ensure that the entire genome is replicated precisely once in each cell cycle. In human cells, this requires that tens of thousands of replication origins are activated exactly once per cell cycle. Failure to do so can lead to cell death or genome rear...

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Detalles Bibliográficos
Autor principal: Diffley, John F. X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203456/
https://www.ncbi.nlm.nih.gov/pubmed/22084381
http://dx.doi.org/10.1098/rstb.2011.0073