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Efficient internal exon recognition depends on near equal contributions from the 3′ and 5′ splice sites
Pre-mRNA splicing is carried out by the spliceosome, which identifies exons and removes intervening introns. In vertebrates, most splice sites are initially recognized by the spliceosome across the exon, because most exons are small and surrounded by large introns. This gene architecture predicts th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203598/ https://www.ncbi.nlm.nih.gov/pubmed/21795381 http://dx.doi.org/10.1093/nar/gkr481 |