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Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery
Major eukaryotic genomic elements, including the ribosomal DNA (rDNA), are composed of repeated sequences with well-defined copy numbers that must be maintained by regulated recombination. Although mechanisms that instigate rDNA recombination have been identified, none are directional and they there...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203602/ https://www.ncbi.nlm.nih.gov/pubmed/21768125 http://dx.doi.org/10.1093/nar/gkr589 |