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Protective effects of L-type fatty acid-binding protein (L-FABP) in proximal tubular cells against glomerular injury in anti-GBM antibody-mediated glomerulonephritis

Background. In glomerulonephritis (GN), an overload of free fatty acids (FFA) bound to albumin in urinary protein may induce oxidative stress in the proximal tubules. Human liver-type fatty acid-binding protein (hL-FABP) expressed in human proximal tubules, but not rodents, participates in intracell...

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Detalles Bibliográficos
Autores principales: Kanaguchi, Yasuhiko, Suzuki, Yusuke, Osaki, Ken, Sugaya, Takeshi, Horikoshi, Satoshi, Tomino, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203629/
https://www.ncbi.nlm.nih.gov/pubmed/21525165
http://dx.doi.org/10.1093/ndt/gfr110