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Protective effects of L-type fatty acid-binding protein (L-FABP) in proximal tubular cells against glomerular injury in anti-GBM antibody-mediated glomerulonephritis
Background. In glomerulonephritis (GN), an overload of free fatty acids (FFA) bound to albumin in urinary protein may induce oxidative stress in the proximal tubules. Human liver-type fatty acid-binding protein (hL-FABP) expressed in human proximal tubules, but not rodents, participates in intracell...
Autores principales: | Kanaguchi, Yasuhiko, Suzuki, Yusuke, Osaki, Ken, Sugaya, Takeshi, Horikoshi, Satoshi, Tomino, Yasuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203629/ https://www.ncbi.nlm.nih.gov/pubmed/21525165 http://dx.doi.org/10.1093/ndt/gfr110 |
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