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The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degeneration

BACKGROUND: Mounting evidence supports a significant role of inflammation in Parkinson's disease (PD) pathophysiology, with several inflammatory pathways being suggested as playing a role in the dopaminergic degeneration seen in humans and animal models of the disease. These include tumor necro...

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Detalles Bibliográficos
Autores principales: Drouin-Ouellet, Janelle, Gibrat, Claire, Bousquet, Mélanie, Calon, Frédéric, Kriz, Jasna, Cicchetti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203853/
https://www.ncbi.nlm.nih.gov/pubmed/21989292
http://dx.doi.org/10.1186/1742-2094-8-137