HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines

BACKGROUND: Hepatocyte Nuclear Factor 1α (HNF1α) is an atypical homeodomain-containing transcription factor that transactivates liver-specific genes including albumin, α-1-antitrypsin and α- and β-fibrinogen. Biallelic inactivating mutations of HNF1A have been frequently identified in hepatocellular...

Descripción completa

Detalles Bibliográficos
Autores principales: Pelletier, Laura, Rebouissou, Sandra, Vignjevic, Danijela, Bioulac-Sage, Paulette, Zucman-Rossi, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203860/
https://www.ncbi.nlm.nih.gov/pubmed/21975049
http://dx.doi.org/10.1186/1471-2407-11-427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203860/
https://www.ncbi.nlm.nih.gov/pubmed/21975049
http://dx.doi.org/10.1186/1471-2407-11-427

Ejemplares similares