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HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines

BACKGROUND: Hepatocyte Nuclear Factor 1α (HNF1α) is an atypical homeodomain-containing transcription factor that transactivates liver-specific genes including albumin, α-1-antitrypsin and α- and β-fibrinogen. Biallelic inactivating mutations of HNF1A have been frequently identified in hepatocellular...

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Detalles Bibliográficos
Autores principales:	Pelletier, Laura, Rebouissou, Sandra, Vignjevic, Danijela, Bioulac-Sage, Paulette, Zucman-Rossi, Jessica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203860/ https://www.ncbi.nlm.nih.gov/pubmed/21975049 http://dx.doi.org/10.1186/1471-2407-11-427

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