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Differential Requirement for Cathepsin D for Processing of the Full Length and C-Terminal Fragment of the Malaria Antigen MSP1

Merozoite Surface Protein 1 is expressed on the surface of malaria merozoites and is important for invasion of the malaria parasite into erythrocytes. MSP1-specific CD4 T cell responses and antibody can confer protective immunity in experimental models of malaria. In this study we explore the contri...

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Detalles Bibliográficos
Autores principales: Tulone, Calogero, Sponaas, Anne-Marit, Raiber, Eun-Ang, Tabor, Alethea B., Langhorne, Jean, Chain, Benny M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203867/
https://www.ncbi.nlm.nih.gov/pubmed/22053177
http://dx.doi.org/10.1371/journal.pone.0024886