The FSHD Atrophic Myotube Phenotype Is Caused by DUX4 Expression

BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is linked to deletions in 4q35 within the D4Z4 repeat array in which we identified the double homeobox 4 (DUX4) gene. We found stable DUX4 mRNAs only derived from the most distal D4Z4 unit and unexpectedly extended to the flanking pLAM region...

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Detalles Bibliográficos
Autores principales: Vanderplanck, Céline, Ansseau, Eugénie, Charron, Sébastien, Stricwant, Nadia, Tassin, Alexandra, Laoudj-Chenivesse, Dalila, Wilton, Steve D., Coppée, Frédérique, Belayew, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203905/
https://www.ncbi.nlm.nih.gov/pubmed/22053214
http://dx.doi.org/10.1371/journal.pone.0026820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203905/
https://www.ncbi.nlm.nih.gov/pubmed/22053214
http://dx.doi.org/10.1371/journal.pone.0026820

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