IFI16 Protein Mediates the Anti-inflammatory Actions of the Type-I Interferons through Suppression of Activation of Caspase-1 by Inflammasomes

BACKGROUND: Type-I interferons (IFNs) are used to treat certain inflammatory diseases. Moreover, activation of type-I IFN-signaling in immune cells inhibits the production of proinflammatory cytokines and activation of inflammasomes. However, the molecular mechanisms remain largely unknown. Upon sen...

Descripción completa

Detalles Bibliográficos
Autores principales: Veeranki, Sudhakar, Duan, Xin, Panchanathan, Ravichandran, Liu, Hongzhu, Choubey, Divaker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203938/
https://www.ncbi.nlm.nih.gov/pubmed/22046441
http://dx.doi.org/10.1371/journal.pone.0027040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203938/
https://www.ncbi.nlm.nih.gov/pubmed/22046441
http://dx.doi.org/10.1371/journal.pone.0027040

Ejemplares similares