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IFI16 Protein Mediates the Anti-inflammatory Actions of the Type-I Interferons through Suppression of Activation of Caspase-1 by Inflammasomes

BACKGROUND: Type-I interferons (IFNs) are used to treat certain inflammatory diseases. Moreover, activation of type-I IFN-signaling in immune cells inhibits the production of proinflammatory cytokines and activation of inflammasomes. However, the molecular mechanisms remain largely unknown. Upon sen...

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Detalles Bibliográficos
Autores principales:	Veeranki, Sudhakar, Duan, Xin, Panchanathan, Ravichandran, Liu, Hongzhu, Choubey, Divaker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203938/ https://www.ncbi.nlm.nih.gov/pubmed/22046441 http://dx.doi.org/10.1371/journal.pone.0027040

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