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PROP1 and CTNNB1 expression in adamantinomatous craniopharyngiomas with or without β-catenin mutations

INTRODUCTION: Activating mutations in exon 3 of the β-catenin gene are involved in the pathogenesis of adamantinomatous craniopharyngiomas. Recently, the interaction between β-catenin and PROP1 has been shown to be responsible for pituitary cell lineage determination. We hypothesized that dysregulat...

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Detalles Bibliográficos
Autores principales: Cani, Carolina M.G., Matushita, Hamilton, Carvalho, Luciani R. S., Soares, Ibere C., Brito, Luciana P., Almeida, Madson Q., Mendonça, Berenice B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203954/
https://www.ncbi.nlm.nih.gov/pubmed/22086512
http://dx.doi.org/10.1590/S1807-59322011001100001