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β-Actin specifically controls cell growth, migration, and the G-actin pool

Ubiquitously expressed β-actin and γ-actin isoforms play critical roles in most cellular processes; however, their unique contributions are not well understood. We generated whole-body β-actin–knockout (Actb(−/−)) mice and demonstrated that β-actin is required for early embryonic development. Lethal...

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Detalles Bibliográficos
Autores principales: Bunnell, Tina M., Burbach, Brandon J., Shimizu, Yoji, Ervasti, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204067/
https://www.ncbi.nlm.nih.gov/pubmed/21900491
http://dx.doi.org/10.1091/mbc.E11-06-0582