Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex

Sec1/Munc18 proteins play a fundamental role in multiple steps of intracellular membrane trafficking. Dual functions have been attributed to Munc18-1: it can act as a chaperone when it interacts with monomeric syntaxin 1A, and it can activate soluble N-ethylmaleimide-sensitive factor attachment prot...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Kümmel, Daniel, Coleman, Jeff, Melia, Thomas J., Giraudo, Claudio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204075/
https://www.ncbi.nlm.nih.gov/pubmed/21900493
http://dx.doi.org/10.1091/mbc.E11-02-0150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204075/
https://www.ncbi.nlm.nih.gov/pubmed/21900493
http://dx.doi.org/10.1091/mbc.E11-02-0150

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