The Discovery of LOX-1, its Ligands and Clinical Significance

LOX-1 is an endothelial receptor for oxidized low-density lipoprotein (oxLDL), a key molecule in the pathogenesis of atherosclerosis.The basal expression of LOX-1 is low but highly induced under the influence of proinflammatory and prooxidative stimuli in vascular endothelial cells, smooth muscle ce...

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Detalles Bibliográficos
Autores principales: Yoshimoto, Ryo, Fujita, Yoshiko, Kakino, Akemi, Iwamoto, Shin, Takaya, Tomohide, Sawamura, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204104/
https://www.ncbi.nlm.nih.gov/pubmed/21805404
http://dx.doi.org/10.1007/s10557-011-6324-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204104/
https://www.ncbi.nlm.nih.gov/pubmed/21805404
http://dx.doi.org/10.1007/s10557-011-6324-6

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