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Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts
BACKGROUND: The kynurenine pathway (KP) is the main route of tryptophan degradation in the human body and generates several neuroactive and immunomodulatory metabolites. Altered levels of KP-metabolites have been observed in neuropsychiatric and neurodegenerative disorders as well as in patients wit...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204223/ https://www.ncbi.nlm.nih.gov/pubmed/21982155 http://dx.doi.org/10.1186/1476-9255-8-25 |