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Gene expression during normal and FSHD myogenesis

BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to contraction of an array of tandem 3.3-kb repeats (D4Z4) at 4q35. Within each repeat unit is a gene, DUX4, that can encode a protein containing two homeodomains. A DUX4 transcript derived from the last repeat un...

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Detalles Bibliográficos
Autores principales: Tsumagari, Koji, Chang, Shao-Chi, Lacey, Michelle, Baribault, Carl, Chittur, Sridar V, Sowden, Janet, Tawil, Rabi, Crawford, Gregory E, Ehrlich, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204225/
https://www.ncbi.nlm.nih.gov/pubmed/21951698
http://dx.doi.org/10.1186/1755-8794-4-67