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Age-related changes in rat bone-marrow mesenchymal stem cell plasticity

BACKGROUND: The efficacy of adult stem cells is known to be compromised as a function of age. This therefore raises questions about the effectiveness of autologous cell therapy in elderly patients. RESULTS: We demonstrated that the expression profile of stemness markers was altered in BM-MSCs derive...

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Detalles Bibliográficos
Autores principales: Asumda, Faizal Z, Chase, P Bryant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204286/
https://www.ncbi.nlm.nih.gov/pubmed/21992089
http://dx.doi.org/10.1186/1471-2121-12-44