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Smad phosphoisoform signaling specificity: the right place at the right time

Transforming growth factor (TGF)-β antagonizes mitogenic Ras signaling during epithelial regeneration, but TGF-β and Ras act synergistically in driving tumor progression. Insights into these apparently contradictory effects have come from recent detailed analyses of the TGF-β signaling process. Here...

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Detalles Bibliográficos
Autor principal: Matsuzaki, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204345/
https://www.ncbi.nlm.nih.gov/pubmed/21798854
http://dx.doi.org/10.1093/carcin/bgr172