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The Frequency of A1298C and C677T Polymorphisms of the Methylentetrahydrofolate Gene in Turkish Patients with Rheumatoid Arthritis: Relationship with Methotrexate Toxicity

The C677T and A1298C polymorphisms of methylenetatrahydrofolate reductase (MTHFR) gene are reported to have a relationship to methotrexate (MTX) metabolism, with conflicting results. The aim of this study was to determine the frequency of MTHFR C677 T and A1298C gene polymorphisms in a group of Turk...

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Detalles Bibliográficos
Autores principales: Taşbaş, Özgür, Borman, Pınar, Gürhan Karabulut, Halil, Tükün, Ajlan, Yorgancıoğlu, Rezan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204425/
https://www.ncbi.nlm.nih.gov/pubmed/22046205
http://dx.doi.org/10.2174/1874312901105010030